Defrost salmon in refrigerator overnight.
Preheat oven to 425 degrees.
Pat salmon dry with paper towels. Place salmon in a sealable bag or medium bowl.
In a small bowl or measuring cup, mix garlic, ginger, red pepper flakes, sesame oil, soy sauce and honey.
Pour half of the marinade on the salmon. Save the other half for later.
Let the salmon marinate in the refrigerator for at least 30 minutes.
Once salmon has marinated, place on baking sheet or in oven-safe glass dish. Pour remaining marinade over salmon, then bake for 10 minutes or until salmon flakes easily.
Remove from oven. Sprinkle sesame seeds on salmon as garnish.